Endocrine Abstracts

Introduction: Pheochromocytoma is an uncommon tumor. Non-classical forms can make diagnosis difficult and delay correct management strategies.Case report: A 20-years old caucasian male presented to the emergency room with unproductive cough, fever and tiredness for 7 days. He was eupneic, afebrile, BP 176/115 mmHg, 104 bpm with inspiratory crepitations in the left lung base. Leucocyte–14.1×109/l (N 70%); platelets – 659×10<...

IntroductionMultifocality is a common finding in papillary thyroid carcinoma (PTC), but its biological significance is not well established. In some cases not all foci present the same histological pattern.ObjectiveTo study the different histological patterns and molecular profiles of multifocal PTC (mPTC).Material and methodsAll patients with a confirmed diagnosi...

BackgroundTranssphenoidal surgery is in general the preferred first-line treatment for patients with macroadenomas except for prolactinomas, which is mainly indicated when the treatment with dopamine agonists (DA) fails. However, in those patients resistant to DA (i.e. volume reduction ObjectiveTo identify predictors of DA resistance in order...

Background: We observed patients with well-differentiated NETs who received PRRT with 177Lu-dotatate and later developed rapid disease progression with biopsy-proven histologic transformation to NECs, an outcome that has not been previously described. In this series, we characterize the clinicopathologic features and outcomes of patients whose tumors underwent poorly-differentiated transformation.Methods: After obtaining IRB approval, we condu...

Objective: Pituitary apoplexy (PA) is a rare, sometimes life-threatening clinical syndrome. However, some cases are subclinical (SPA), just revealed by MR performed during the follow-up of known pituitary adenomas or due to other conditions. Our aims were to describe the clinical characteristics and evolution of the patients with SPA compared with patients with acute PA (APA). We also compare the results of surgery vs conservative management in the APA group.<p class="abst...